Since its initial discovery in the 1800s until recently, myelin was considered a simple insulator for axons, and its formation was believed to be regulated by predetermined biochemical and cellular processes. Moreover, both oligodendrocytes and the myelin they generate were considered to be static components of the nervous system. However, recent studies have revealed that oligodendrocyte development and myelination are highly dynamic processes that continue throughout adult life, are influenced by experience and neuronal activity, and contribute to cognitive function and behavior

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Abstract: Objective: Constipation is often overlooked in patients with schizophrenia. We examined their awareness of constipation and whether they reported it to their psychiatrists.Method: Five hundred three inpatients with schizophrenia (International Classification of Diseases, 10th Revision) were interviewed about their recent bowel movements and evaluated for the diagnostic criteria for functional constipation. If constipation was present, patients were asked if they were aware of it and had reported it to their psychiatrists in charge

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Abstract: Objective: Constipation is often overlooked in patients with schizophrenia. We examined their awareness of constipation and whether they reported it to their psychiatrists.Method: Five hundred three inpatients with schizophrenia (International Classification of Diseases, 10th Revision) were interviewed about their recent bowel movements and evaluated for the diagnostic criteria for functional constipation. If constipation was present, patients were asked if they were aware of it and had reported it to their psychiatrists in charge.

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Abstract: Objective: To examine suicidal ideation in a sample of German primary care patients.Methods: We conducted a cross-sectional study and included 1455 primary care patients who visited 1 of 41 general practitioners (GPs) working at 19 different sites. Suicidal ideation and psychopathology were assessed with the Patient Health Questionnaire (PHQ) in an anonymous screening together with health care utilization.Results: One hundred seventy-one (11.8%) of 1455 patients endorsed the suicidal ideation item of the PHQ.

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