Abstract: Objective: Cardiovascular side effects of lithium have been reported to occur mainly at higher-than-therapeutic serum levels. We aimed to investigate the impact of the long-term lithium use on electrocardiogram (ECG) parameters in association with the serum levels in patients with bipolar disorder (BD) and in healthy controls (HCs) serving as the reference group.Methods: The study sample consisted of 53 euthymic BD type I patients on lithium monotherapy at therapeutic serum levels (M=0.76, S.D.=0.14, range=0.41–1.09 mmol/l) for at least 12 months and 45 HCs.
Abstract: Objectives: To examine the epidemiology of and possible risk factors for skin diseases in patients with schizophrenia.Methods: All of 337 patients with schizophrenia were recruited from the therapeutic community of a psychiatric hospital and underwent a detailed skin examination. The National Health Insurance Research Database (NHIRD) was used to compare the prevalence of skin diseases between patients with schizophrenia and those without.Results: In the clinical survey, fungal infection (61.4%) and dermatitis (46.9%) were the most common skin diseases.
About 50%–60% of patients with depression fail to completely recover on an antidepressant medication according to the Sequenced Treatment Alternatives to Relieve Depression study . Combination therapy, which involves addition of an antidepressant agent with a different chemical profile to the therapeutic regimen, forms an important treatment strategy . However, combination treatment is usually found to be associated with greater side effects
Abstract: Objective: A growing number of health information technologies (HIT) are being developed and tested to address mental health conditions. HIT includes Internet and smartphone programs or apps, text messaging protocols and telepsychiatry. We reviewed the promise and evidence that HIT can expand access to mental health care and reduce disparities in use of services across groups in need.Conclusions: Limited reach of mental health services is a pervasive problem in the United States, and solving it will require innovations that enable us to extend our clinical reach into underserved populations without significantly expanding our workforce.