Ten to 15% of the population use benzodiazepines in any given year, and 2% use benzodiazepines chronically. However, benzodiazepine use disorder is more prevalent in individuals who abuse other substances .

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Importance Controlled family studies have consistently found that obsessive-compulsive disorder (OCD) aggregates in families but have typically relied on samples recruited from specialist clinics. Furthermore, previous studies could not disentangle genetic from environmental factors contributing to the observed familiality.

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