Director’s Blog NIMH just reached a milestone — our first grant was awarded 65 years ago last month. Rather than celebrating, this anniversary has been allowed to pass quietly. With so much progress in genomics and neuroscience, we at NIMH have mostly been trying to keep up

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Director’s Blog One of the most influential trials in cardiology over the past 25 years was the GISSI 1 study, which demonstrated the beneficial effects of administering a medication called streptokinase after a heart attack. 2 GISSI involved more than 11, 000 patients in 176 coronary care units over 17 months. Its total cost was less than $500, 000.

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Director’s Blog Let’s start with some good news. Over the past few decades in the United States, we have seen dramatic reductions in mortality due to coronary artery disease (an over 60 percent reduction, with 1.1 millions deaths averted each year), AIDS (a 40 percent reduction, with over 30,000 deaths averted each year), and stroke (a 30 percent reduction, with over 20,000 deaths averted each year). Indeed, last month AIDS was declared a chronic disease, recognizing that a young person who becomes infected with HIV will likely survive for decades and die of other causes

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Director’s Blog In a commentary just published on innovation in health care, Narayan and colleagues describe the need for integrated solutions to mental health care. 1 Moving beyond “magic bullets” and the magical thinking of a single intervention for a complex problem, they recommend a comprehensive model that includes early detection, better access to care, monitoring, and patient-reported outcomes. None of this would be particularly innovative, except that Narayan and his colleagues all work for a pharmaceutical company.

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