For pediatricians and parents, one of the most important tools is decidedly low tech. The growth chart, a simple graph of the trajectory of the normal range of height, weight, and head circumference across age, is a vital tool for detecting problems in development. Even when a child is in the normal range, identifying a change from the 80 th percentile at age 6 to the 20 th percentile at age 8 can indicate a problem.

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Importance Psychosis-risk studies have examined help-seeking adolescents and young adults. Population-based studies evaluating psychotic symptoms and neurocognitive performance across childhood are needed for “growth charting” cognitive development.

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Abstract: Objective: Psychosis is a recognized but often forgotten side effect of many commonly prescribed medications.Method: A case of psychosis in a 27-year-old female related to metronidazole treatment is presented along with review of possible mechanisms.Results: The onset and resolution of psychosis appeared to coincide with metronidazole treatment.Conclusions: Clinicians should be aware of medication-related psychosis.

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Nancy E. Broskie, MD

Private Practice, Salem, OR; Affiliate Assistant Professor, Oregon Health and Science University, Portland, OR

First published in Psychiatry Weekly, August 2013, 8(17).

Introduction

Coenzyme Q10 (CoQ10) is an antioxidant supplement that could reduce Parkinsonism,1 aid migraine prophylaxis,2 and increase energy.3 CoQ10 is produced in the body simultaneously with cholesterol, which is inversely related to severity of both depression4 and Parkinsonism.5 Basal ganglia calcification can be caused by hypoparathyroidism with hypocalcemia.6 Two patients with low baseline parathyroid hormone (PTH) and extrapyramidal symptoms tried CoQ10 for energy and migraine prophylaxis, during which time they had transient psychosis that remitted when CoQ10 was discontinued.

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