Low-intensity interventions, such as self-help books and interactive Web sites, may provide a low-cost, first-line treatment option for patients even with severe depression, research suggests. Medscape Medical News

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A nicotine vaccine reduces the amount of nicotine that reaches the brain, subsequent cigarette use and cravings, a new study shows. Medscape Medical News

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Director’s Blog Let’s start with some good news. Over the past few decades in the United States, we have seen dramatic reductions in mortality due to coronary artery disease (an over 60 percent reduction, with 1.1 millions deaths averted each year), AIDS (a 40 percent reduction, with over 30,000 deaths averted each year), and stroke (a 30 percent reduction, with over 20,000 deaths averted each year). Indeed, last month AIDS was declared a chronic disease, recognizing that a young person who becomes infected with HIV will likely survive for decades and die of other causes

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In the largest genetic study of psychiatric illness to date, scientists have discovered genetic links between 5 major psychiatric disorders. Medscape Medical News

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Retinal blood vessel changes may serve as biomarkers for amyloid plaque in the brain, which in turn may signal early stages of Alzheimer’s disease, new research shows. Medscape Medical News

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