Abstract: Objectives: To examine the epidemiology of and possible risk factors for skin diseases in patients with schizophrenia.Methods: All of 337 patients with schizophrenia were recruited from the therapeutic community of a psychiatric hospital and underwent a detailed skin examination. The National Health Insurance Research Database (NHIRD) was used to compare the prevalence of skin diseases between patients with schizophrenia and those without.Results: In the clinical survey, fungal infection (61.4%) and dermatitis (46.9%) were the most common skin diseases.
Abstract: Objective: Depression is a highly prevalent disorder that is associated with disability. The aim of this study was to determine the relationship between depression and hyperlipidemia, and whether the onset of depression is associated with administering statins to patients with hyperlipidemia.Material and Methods: The data analyzed in this study were retrieved from the National Health Insurance Research Database (NHIRD) in Taiwan.
Abstract: Objective: To examine the relationship of poor dental health and depression, controlling for markers of inflammation (C-Reactive Protein; CRP) and adiposity (Body Mass Index; BMI).Method: Data from two National Health and Nutrition Examination Surveys (NHANES) (2005–2008) were utilized (n=10, 214). Dental health was assessed using the Oral Health Questionnaire (OHQ). Depression was measured using the Patient Health Questionnaire-9 (PHQ-9), where cases were identified using a cut off score of 10 or above.
Abstract: Objective: Persons with thoughts of self-harm may need evaluation for suicide risk. We examine the prevalence of thoughts of self-harm and whether persons with thoughts of self-harm are identified when two-stage depression screening is used.Methods: Data are from the 2005–2010 National Health and Nutrition Examination Surveys. Persons responding positively to question nine of the Patient Health Questionnaire-9 (PHQ-9) are identified as having thoughts of self-harm.
Abstract: Objective: The objective was to estimate the prevalence of both dementia and depression among community-dwelling older Americans and to determine if hospitalization is independently associated with dementia or depression in this population.Method: This cross-sectional study utilized data from a nationally representative, population-based sample of 7197 community-dwelling adults ?65 years old interviewed in 2011 as part of the National Health and Aging Trends Study. Information on hospitalizations was obtained from self- or proxy-report.
Importance Genetic markers at the gene encoding the metabotropic glutamate receptor 3 (GRM3) showed allelic association with bipolar disorder. Objective To screen the GRM3 gene and adjacent control regions of genomic DNA in volunteers with bipolar affective disorder for mutations increasing susceptibility to bipolar disorder. Design Sequencing and high-resolution melting curve analysis of DNA followed by genotyping was carried out in 1099 patients with bipolar affective disorder and 1152 healthy comparator individuals.