Daily cycles of gene expression exist in healthy human brains, but these patterns are disrupted in clinically depressed individuals, new research shows. Medscape Medical News

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Neuroimaging studies show that the brains of people with treatment-resistant depression show altered metabolic activity in areas known to be linked to depression early after vagus nerve stimulation. Medscape Medical News

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New “meta-guidelines” combining recommendations from several expert organizations on the management and treatment of schizophrenia have been released. Medscape Medical News

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After almost a decade of development and more than 2 years of frequently searing controversy, the DSM-5 has been officially released. Medscape Medical News

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In a new commentary, DSM-IV chair Allen Frances is highly critical of newly released DSM-5 and advises physicians use it “cautiously, if at all.” Medscape Medical News

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Cannabis users who start smoking the drug in adolescence show an irreparable decline in IQ, new research shows. Medscape Medical News

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An epidemiologist applied some of the lessons learned battling infectious disease epidemics in Africa to street violence in Chicago. Medscape Medical News

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Elevated blood levels of inflammatory proteins may serve as a biomarker for suicidal risk in individuals with major depression. Medscape Medical News

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With a mean annual income of $186, 000, US psychiatrists are in the bottom third of the compensation ranks compared with other specialists, according to Medscape’s 2013 Psychiatrist Compensation Report. Medscape Medical News

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Director’s Blog Last week’s autism news was about prevalence. The CDC reported a 78 percent increase in autism prevalence since 2002. This week’s autism news is about genetics— three papers in Nature describe new genes associated with autism

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