Importance The single-nucleotide polymorphism rs1344706 in the zinc finger protein 804A gene ( ZNF804A ) shows genome-wide association with schizophrenia and bipolar disorder. Little is known regarding the expression of ZNF804A and the functionality of rs1344706. Objectives To characterize ZNF804A expression in human brain and to investigate how it changes across the life span and how it is affected by rs1344706, schizophrenia, bipolar disorder, and major depressive disorder.
Abstract: Objectives: To examine the epidemiology of and possible risk factors for skin diseases in patients with schizophrenia.Methods: All of 337 patients with schizophrenia were recruited from the therapeutic community of a psychiatric hospital and underwent a detailed skin examination. The National Health Insurance Research Database (NHIRD) was used to compare the prevalence of skin diseases between patients with schizophrenia and those without.Results: In the clinical survey, fungal infection (61.4%) and dermatitis (46.9%) were the most common skin diseases.
The mental health evaluation of the patient requesting physician-assisted death (PAD) has two goals, often written into laws that permit PAD. One goal is to ensure that the patient does not have a potentially treatable mental disorder influencing the decision to hasten death. Most discussions of relevant mental disorders point to the roles of anxiety and depression, particularly major depressive disorder, in which possibly treatable and reversible hopelessness, sadness and anhedonia may impact views about suicide
Abstract: Cannabis in its various forms has been known since time immemorial, the use of which has been rising steadily in India. ‘Bad trips’ have been documented after cannabis use, manifestations ranging from vague anxiety and fear to profoundly disturbing states of terror and psychosis.