Importance Alterations in glutamatergic neurotransmission have been postulated to be a key pathophysiologic mechanism in schizophrenia. Objective To evaluate hippocampal volumetric measures and neurometabolites in unmedicated patients with schizophrenia and the correlations between these markers.

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Importance Posttraumatic stress disorder (PTSD) is a pervasive and often debilitating condition that affects many individuals in the general population and military service members. Effective treatments for PTSD are greatly needed for both veterans returning from Iraq and Afghanistan and veterans of other eras.

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Importance There are limited data on the extent to which suicide mortality is associated with specific pain conditions. Objective To examine the associations between clinical diagnoses of noncancer pain conditions and suicide among individuals receiving services in the Department of Veterans Affairs Healthcare System. Design Retrospective data analysis

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Director’s Blog Today, on World Suicide Prevention Awareness Day, an updated National Strategy for Suicide Prevention is being released amidst a public health landscape that has changed thanks in part to the focus brought to suicide by the first national strategy issued 11 years ago. Since the first version was issued, the Suicide Prevention Lifeline was established, Federal and State legislation has been passed that advances suicide prevention planning and programming, and the Suicide Prevention Resource Center was established, among other efforts.

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