Abstract: Objective: The prevalence of depression in multiple sclerosis (MS) is known to be elevated, but nearly all available studies have estimated period prevalence. The objective of this study was to estimate the point prevalence of depression in a representative community sample using the Patient Health Questionnaire, Brief (PHQ-9).Methods: The data source for this study was the Survey of Living with Neurological Conditions in Canada, which was derived from a representative sample of household residents.Results: The sample included 630 respondents with MS. With application of the standard PHQ-9 cut-point (10+) the prevalence of depression was 26.0% (95% CI 18.9 – 33.0%).

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