Abstract: Background: The aim was to measure symptoms of depression and anxiety in patients with bronchiectasis and evaluate their relationship with a Mediterranean diet.Methods: This cross-sectional study recruited patients with bronchiectasis at four Spanish centers. Patients completed the hospital anxiety and depression scale (HADS) and the Mediterranean diet questionnaire (Predimed). Demographic, health and outcome data were recorded from medical charts

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Abstract: Objective: To examine the relationship of poor dental health and depression, controlling for markers of inflammation (C-Reactive Protein; CRP) and adiposity (Body Mass Index; BMI).Method: Data from two National Health and Nutrition Examination Surveys (NHANES) (2005–2008) were utilized (n=10, 214). Dental health was assessed using the Oral Health Questionnaire (OHQ). Depression was measured using the Patient Health Questionnaire-9 (PHQ-9), where cases were identified using a cut off score of 10 or above.

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Importance Pediatric anxiety disorders are highly prevalent and impairing and are considered gateway disorders in that they predict adult psychiatric problems. Although they can be effectively treated in the short term, data are limited on the long-term outcomes in treated children and adolescents, particularly those treated with medication.

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Importance Studies have shown that attention-deficit/hyperactivity disorder (ADHD) is associated with transport accidents, but the magnitude of the association remains unclear. Most important, it is also unclear whether ADHD medication reduces this risk.

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Abstract: Objectives: Individuals with bipolar disorder (BP) are often misdiagnosed with major depressive disorder (MDD). In this study, we developed a Chinese version of 15-point hypomania scale (HCL-15) in order to determine its sensitivity and specificity in the diagnosis of BP and BP-II in particular.Methods: A total of 623 individuals suffering a major depressive episode (MDE) were systematically interviewed with both Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Patient Edition, and HCL-15. A cutoff score of 8 or more in HCL-15 was suggested for BP.Results: Of the 623 depressed patients, 115 (18.5%) actually required a diagnosis of BP-I, and another 159 (25.5%) could be more appropriately diagnosed with BP-II, according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria.

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Abstract: Objective: The objective was to investigate impulsiveness among chronic hepatitis C (CHC) patients and its association with sociodemographic, clinical and psychopathological factors.Method: Ninety-one CHC individuals were enrolled in a cross-sectional study at a Brazilian public university-based outpatient’s service for infectious diseases. They were assessed using the Barrat Impulsiveness Scale, Brief Fatigue Inventory, Beck Depression Inventory and Hamilton Anxiety Scale. Structured psychiatric interview was performed according to the Mini International Neuropsychiatric Interview.

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Abstract: Objective: The aim of this study is to investigate the development of depression during interferon-alpha (IFN-?) therapy and the variations in the expression of the serotonin receptor (5-HTR) and transporter (5-HTT) in hepatitis C patients.Method: Hepatitis C patients (n=277) were given the Mini International Neuropsychiatric Interview at the end of IFN-? therapy. Three polymorphisms were genotyped: the serotonin transporter repeat length polymorphic region [5-HTT gene-linked polymorphic region (5-HTTLPR)], as well as SNPs rs25531 and rs6295, located within the 5-HTTLPR and the transcriptional control region of the 5-HTR1A gene, respectively.Results: The diagnosis of current depression, which was associated with IFN-?-related depression (P

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In the above article, in Section “3.2. Clinical Outcomes,” the sentence: “Within-group effect sizes for these measures ranged between 0.08 (HADS anxiety, active control group) and 0.63 (SOMS, ASTPP)” needs to be corrected as follows: “Within-group effect sizes for these measures ranged between 0.08 (HADS anxiety, active control group) and 0.52 (PID, ASTPP).”

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In a previous post I described the growing contrast between the patient community for whom “time = lives” and the academic community for whom “success = papers and grant funding.” This apparent clash of cultures is important for NIMH. Each year, we spend roughly $1B of taxpayer funds to support research in academia.

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Introduction: Huntington disease (HD) is an inherited, progressive, autosomal dominant disorder. Some patients develop severe chorea or cognitive symptoms.

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