Abstract: Objective: This cross-sectional study considered whether variability in respiratory functioning could explain the variability in walking ability of individuals with schizophrenia taking into account variability in body mass index (BMI), lifestyle factors, psychiatric symptoms, antipsychotic medication use and muscular fitness.Method: Eighty patients with schizophrenia and 40 age, gender and BMI matched controls underwent a spirometry, 6-minute walk test (6MWT) and completed the International Physical Activity Questionnaire. Patients were additionally screened for psychiatric symptoms.Results: Compared to health controls, patients with schizophrenia achieved a lower distance on the 6MWT (583.6±109.7m versus 710.6±108.4m, p

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